Laboratory for Molecular Diagnostics
Center for Nephrology and Metabolic Disorders

Nephritic syndrome

A complex of nephrological symptoms dominated by haematuria and hypertension is called nephritic syndrome.

Diagnosis

The diagnosis is made by the urinary sediment. Glomerular dysmorphic erythrocytes, acanthocytes, are found predominantly. Also red blood cell casts may be present. Often accompanied by mild to moderate proteinuria, oedema, hypertension, and elevated serum creatinine.

Systematic

Hereditary glomerular disease
Fibronectin glomerulopathy
Glomerulonephritis
Glomerulosclerosis
Lipoprotein glomerulopathy
Myoclonus-nephropathy syndrome
Nephritic syndrome
CFHR5 Nephropathy
CFHR5
Glomerular basement membrane disorders
Alport Syndrome
COL4A3
COL4A4
COL4A5
HANAC syndrome
COL4A1
COL4A2
Leiomyomatosis with Alport syndrome, Smooth muscle tumors and Alport syndrome
COL4A5
COL4A6
MYH9 related disorders
MYH9
Nail-patella syndrome
LMX1B
Nephropathy with pretibial epidermolysis bullosa and deafness
CD151
PXDN
Thin basement membrane nephropathy
COL4A3
COL4A4
COL4A5
Nephrotic syndrome

References:

1.

Weber S et al. (2005) Recurrence of focal-segmental glomerulosclerosis in children after renal transplantation: clinical and genetic aspects.

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2.

Tryggvason K et al. (2006) Thin basement membrane nephropathy.

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3.

Gubler MC et al. (2003) Podocyte differentiation and hereditary proteinuria/nephrotic syndromes.

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4.

Winn MP et al. (2003) Approach to the evaluation of heritable diseases and update on familial focal segmental glomerulosclerosis.

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