Clinical feature: 

Definition: Uric acid nephropathy is characterized by accumulation of uric acid in renal tissues and recurrent uric acid nephrolithiasis. The pathogenesis includes uric acid overproduction and excessive renal excretion.

Diagnostics: 

Differential: We also find interstitial substances and recurrent urolithiasis in uric acid nephropathy, but by contrast these are not visible to x-ray detectors.  » » » 

Literature: 

Tausche AK et al. (2009) Gout--current diagnosis and treatment.
Jabur WL et al. (2009) Acute urate nephropathy precipitated by acute diarrhea.
Chen YC et al. () A preliminary investigation of the association between serum uric acid and impaired renal function.
Mohandas R et al. (2008) Uric acid levels increase risk for new-onset kidney disease.
Edwards NL et al. (2008) The role of hyperuricemia and gout in kidney and cardiovascular disease.
Hladnik U et al. (2008) Variable expression of HPRT deficiency in 5 members of a family with the same mutation.
Sánchez-Lozada LG et al. (2008) Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia.