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Alloimmune thrombocytopenia
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Alloimmune thrombocytopenia

Clinical feature: 

Definition: Alloimmune thrombocytopenia is a blleding disorder of the newborn that results from maternal allo-antibodies against fetal platelets. The reason for these allo-antibodies is the fetus bears a platelet antigen inherited from its father for which the mother did not develop immuno-tolerance.

Systematic link table: 

Inherited disorders of platelets
Alloimmune thrombocytopenia
ITGA2B
ITGB3
Bernard-Soulier syndrome
GP1BA
GP1BB
GP9
Thrombasthenia of Glanzmann and Naegeli
ITGA2B
ITGB3

Literature: 

Kher A et al. (2007) The management of thrombosis in pregnancy: role of low-molecular-weight heparin.