Interleukin-13

Wang M et al. (2003) A common IL-13 Arg130Gln single nucleotide polymorphism among Chinese atopy patients with allergic rhinitis.

Heinzmann A et al. (2000) Genetic variants of IL-13 signalling and human asthma and atopy.

Howard TD et al. (2001) Identification and association of polymorphisms in the interleukin-13 gene with asthma and atopy in a Dutch population.

Howard TD et al. (2002) Gene-gene interaction in asthma: IL4RA and IL13 in a Dutch population with asthma.

Morgan JG et al. (1992) The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes.

Smirnov DV et al. (1995) Tandem arrangement of human genes for interleukin-4 and interleukin-13: resemblance in their organization.

Zurawski G et al. (1994) Interleukin 13 elicits a subset of the activities of its close relative interleukin 4.

Minty A et al. (1993) Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses.

Punnonen J et al. (1993) Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells.

McKenzie AN et al. (1993) Interleukin 13, a T-cell-derived cytokine that regulates human monocyte and B-cell function.

Wills-Karp M et al. (1998) Interleukin-13: central mediator of allergic asthma.

Grünig G et al. (1998) Requirement for IL-13 independently of IL-4 in experimental asthma.

Zhu Z et al. (1999) Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production.

Loots GG et al. (2000) Identification of a coordinate regulator of interleukins 4, 13, and 5 by cross-species sequence comparisons.

Lacy DA et al. (2000) Faithful expression of the human 5q31 cytokine cluster in transgenic mice.

Zheng T et al. (2000) Inducible targeting of IL-13 to the adult lung causes matrix metalloproteinase- and cathepsin-dependent emphysema.

Kuperman DA et al. (2002) Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma.

Lanone S et al. (2002) Overlapping and enzyme-specific contributions of matrix metalloproteinases-9 and -12 in IL-13-induced inflammation and remodeling.

Kelly-Welch AE et al. (2003) Interleukin-4 and interleukin-13 signaling connections maps.

He JQ et al. (2003) Genetic variants of the IL13 and IL4 genes and atopic diseases in at-risk children.

Blackburn MR et al. (2003) Adenosine mediates IL-13-induced inflammation and remodeling in the lung and interacts in an IL-13-adenosine amplification pathway.

Zhu Z et al. (2004) Acidic mammalian chitinase in asthmatic Th2 inflammation and IL-13 pathway activation.

Chen W et al. (2004) Functional effect of the R110Q IL13 genetic variant alone and in combination with IL4RA genetic variants.

Hiromatsu Y et al. (2005) Interleukin-13 gene polymorphisms confer the susceptibility of Japanese populations to Graves' disease.

Chen Q et al. (2005) IL-11 receptor alpha in the pathogenesis of IL-13-induced inflammation and remodeling.

Vladich FD et al. (2005) IL-13 R130Q, a common variant associated with allergy and asthma, enhances effector mechanisms essential for human allergic inflammation.

Kouriba B et al. (2005) Analysis of the 5q31-q33 locus shows an association between IL13-1055C/T IL-13-591A/G polymorphisms and Schistosoma haematobium infections.

Fichtner-Feigl S et al. (2006) IL-13 signaling through the IL-13alpha2 receptor is involved in induction of TGF-beta1 production and fibrosis.

LaPorte SL et al. (2008) Molecular and structural basis of cytokine receptor pleiotropy in the interleukin-4/13 system.

Neill DR et al. (2010) Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity.

Wu D et al. (2011) Eosinophils sustain adipose alternatively activated macrophages associated with glucose homeostasis.

Nussbaum JC et al. (2013) Type 2 innate lymphoid cells control eosinophil homeostasis.

Bosurgi L et al. (2017) Macrophage function in tissue repair and remodeling requires IL-4 or IL-13 with apoptotic cells.

NCBI article

OMIM.ORG article

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