Das ANGPTL8-Gen kodiert einen Inhibitor der Lipolyse. Somit ist dieses Gen ein Kandidat für Störungen im Fettstoffwechsel mit überwiegender Hypertriglyceridämie.
Klinisch | Untersuchungsmethoden | Familienuntersuchung |
Bearbeitungszeit | 5 Tage | |
Probentyp | genomische DNS |
Forschung | Untersuchungsmethoden | Direkte Sequenzierung der proteinkodierenden Bereiche eines Gens |
Bearbeitungszeit | 25 Tage | |
Probentyp | genomische DNS |
![]() |
|||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() ![]() |
||
![]() |
![]() |
![]() |
![]() |
1. |
Cefalù AB et al. () Identification of a novel LMF1 nonsense mutation responsible for severe hypertriglyceridemia by targeted next-generation sequencing. ![]() |
2. |
None (2012) Lipasin, a novel nutritionally-regulated liver-enriched factor that regulates serum triglyceride levels. ![]() |
3. |
Quagliarini F et al. (2012) Atypical angiopoietin-like protein that regulates ANGPTL3. ![]() |
4. |
Tseng YH et al. (2014) Chromosome 19 open reading frame 80 is upregulated by thyroid hormone and modulates autophagy and lipid metabolism. ![]() |
5. |
Gusarova V et al. (2014) ANGPTL8/betatrophin does not control pancreatic beta cell expansion. ![]() |
6. |
NCBI article NCBI 55908![]() |
7. |
OMIM.ORG article Omim 616223![]() |
8. |
Wikipedia Artikel Wikipedia DE (Betatrophin)![]() |