Beta-2-adreneger Rezeptor

Tsai HJ et al. (2006) Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmatics.

Meirhaeghe A et al. (2001) The effect of the Gly16Arg polymorphism of the beta(2)-adrenergic receptor gene on plasma free fatty acid levels is modulated by physical activity.

Corbalán MS et al. (2002) The 27Glu polymorphism of the beta2-adrenergic receptor gene interacts with physical activity influencing obesity risk among female subjects.

Bachman ES et al. (2002) betaAR signaling required for diet-induced thermogenesis and obesity resistance.

Evans WE et al. (2003) Pharmacogenomics--drug disposition, drug targets, and side effects.

Harrison T et al. (2003) Erythrocyte G protein-coupled receptor signaling in malarial infection.

Dallongeville J et al. (2003) The Gly16>Arg16 and Gln27>Glu27 polymorphisms of beta2-adrenergic receptor are associated with metabolic syndrome in men.

Odley A et al. (2004) Regulation of cardiac contractility by Rab4-modulated beta2-adrenergic receptor recycling.

Dishy V et al. (2004) Beta2-adrenoceptor Thr164Ile polymorphism is associated with markedly decreased vasodilator and increased vasoconstrictor sensitivity in vivo.

Israel E et al. () Use of regularly scheduled albuterol treatment in asthma: genotype-stratified, randomised, placebo-controlled cross-over trial.

Elefteriou F et al. (2005) Leptin regulation of bone resorption by the sympathetic nervous system and CART.

Contopoulos-Ioannidis DG et al. (2005) Meta-analysis of the association of beta2-adrenergic receptor polymorphisms with asthma phenotypes.

Lönnqvist F et al. (1992) Lipolytic catecholamine resistance due to decreased beta 2-adrenoceptor expression in fat cells.

Rasmussen SG et al. (2007) Crystal structure of the human beta2 adrenergic G-protein-coupled receptor.

Rosenbaum DM et al. (2007) GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.

Cherezov V et al. (2007) High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.

Cagliani R et al. (2009) Diverse evolutionary histories for beta-adrenoreceptor genes in humans.

Nikolaev VO et al. (2010) Beta2-adrenergic receptor redistribution in heart failure changes cAMP compartmentation.

Wilson RH et al. (2010) Evolutionary history of the ADRB2 gene in humans.

Coureuil M et al. (2010) Meningococcus Hijacks a β2-adrenoceptor/β-Arrestin pathway to cross brain microvasculature endothelium.

Rasmussen SG et al. (2011) Structure of a nanobody-stabilized active state of the β(2) adrenoceptor.

Rosenbaum DM et al. (2011) Structure and function of an irreversible agonist-β(2) adrenoceptor complex.

Rasmussen SG et al. (2011) Crystal structure of the β2 adrenergic receptor-Gs protein complex.

Chung KY et al. (2011) Conformational changes in the G protein Gs induced by the β2 adrenergic receptor.

Davare MA et al. (2001) A beta2 adrenergic receptor signaling complex assembled with the Ca2+ channel Cav1.2.

Ni Y et al. (2006) Activation of beta2-adrenergic receptor stimulates gamma-secretase activity and accelerates amyloid plaque formation.

Oakey RJ et al. (1991) Genomic organization of adrenergic and serotonin receptors in the mouse: linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution.

Szefler SJ et al. (1991) Plasma histamine, epinephrine, cortisol, and leukocyte beta-adrenergic receptors in nocturnal asthma.

Yang-Feng TL et al. (1990) Chromosomal organization of adrenergic receptor genes.

Emorine LJ et al. (1987) Structure of the gene for human beta 2-adrenergic receptor: expression and promoter characterization.

Fraser CM et al. (1988) Site-directed mutagenesis of human beta-adrenergic receptors: substitution of aspartic acid-130 by asparagine produces a receptor with high-affinity agonist binding that is uncoupled from adenylate cyclase.

Kobilka BK et al. (1987) cDNA for the human beta 2-adrenergic receptor: a protein with multiple membrane-spanning domains and encoded by a gene whose chromosomal location is shared with that of the receptor for platelet-derived growth factor.

Kobilka BK et al. () An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins.

Sheppard JR et al. (1983) Chromosomal assignment of the gene for the human beta 2-adrenergic receptor.

Turki J et al. (1995) Genetic polymorphisms of the beta 2-adrenergic receptor in nocturnal and nonnocturnal asthma. Evidence that Gly16 correlates with the nocturnal phenotype.

Reihsaus E et al. (1993) Mutations in the gene encoding for the beta 2-adrenergic receptor in normal and asthmatic subjects.

Dewar JC et al. (1997) The glutamine 27 beta2-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families.

Large V et al. (1997) Human beta-2 adrenoceptor gene polymorphisms are highly frequent in obesity and associate with altered adipocyte beta-2 adrenoceptor function.

Martinez FD et al. (1997) Association between genetic polymorphisms of the beta2-adrenoceptor and response to albuterol in children with and without a history of wheezing.

Hopes E et al. (1998) Association of glutamine 27 polymorphism of beta 2 adrenoceptor with reported childhood asthma: population based study.

Krushkal J et al. (1998) Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation.

Luttrell LM et al. (1999) Beta-arrestin-dependent formation of beta2 adrenergic receptor-Src protein kinase complexes.

Yamada K et al. (1999) Polymorphism in the 5'-leader cistron of the beta2-adrenergic receptor gene associated with obesity and type 2 diabetes.

Rohrer DK et al. (1999) Cardiovascular and metabolic alterations in mice lacking both beta1- and beta2-adrenergic receptors.

Maurice JP et al. (1999) Enhancement of cardiac function after adenoviral-mediated in vivo intracoronary beta2-adrenergic receptor gene delivery.

Drysdale CM et al. (2000) Complex promoter and coding region beta 2-adrenergic receptor haplotypes alter receptor expression and predict in vivo responsiveness.

Shenoy SK et al. (2001) Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin.

OMIM.ORG article

NCBI article

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