Molekulargenetisches Labor
Zentrum für Nephrologie und Stoffwechsel

C-X-C Chemokin-Rezeptor Typ 1

IL-8-Rezeptor Typ 1; Interleukin 8-Rezeptor 1

Gentests:

Klinisch Untersuchungsmethoden Familienuntersuchung
Bearbeitungszeit 5 Tage
Probentyp genomische DNS
Klinisch Untersuchungsmethoden Hochdurchsatz-Sequenzierung
Bearbeitungszeit 25 Tage
Probentyp genomische DNS
Forschung Untersuchungsmethoden Direkte Sequenzierung der proteinkodierenden Bereiche eines Gens
Bearbeitungszeit 25 Tage
Probentyp genomische DNS

Verknüpfte Erkrankungen:

HIV-Resistenz
CCR5
CXCR1
HIV 1-Infektionsanfälligkeit
IL10
Mesangioproliferative Glomerulonephritis
CXCR1
IgA-Nephropathie
CFHR1
CFHR3
CFHR5
IgA-Nephropathie Typ 1
IgA-Nephropathie Typ 2
IgA-Nephropathie Typ 3
SPRY2
Komplement C1q-Mangel
C1QA
C1QB
C1QC
Schimke-Dysplasie
SMARCAL1
Wiskott-Aldrich-Syndrom
WAS

Referenzen:

1.

Morris SW et al. (1992) Assignment of the genes encoding human interleukin-8 receptor types 1 and 2 and an interleukin-8 receptor pseudogene to chromosome 2q35.

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2.

Holmes WE et al. (1991) Structure and functional expression of a human interleukin-8 receptor.

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3.

Mollereau C et al. (1993) The high-affinity interleukin 8 receptor gene (IL8RA) maps to the 2q33-q36 region of the human genome: cloning of a pseudogene (IL8RBP) for the low-affinity receptor.

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4.

Lloyd A et al. (1993) Assignment of genes for interleukin-8 receptors (IL8R) A and B to human chromosome band 2q35.

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5.

Palter SF et al. (2001) Interleukin-8 in the human fallopian tube.

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6.

Weathington NM et al. (2006) A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation.

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7.

Vasilescu A et. al. (2007) A haplotype of the human CXCR1 gene protective against rapid disease progression in HIV-1+ patients.

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8.

Hartl D et al. (2007) Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease.

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9.

Ozaltin F et al. (2013) Role of CXCR1 (CKR-1) in inflammation of experimental mesangioproliferative glomerulonephritis.

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10.

NCBI article

NCBI 3577 [^]
11.

OMIM.ORG article

Omim 146929 [^]
12.

Wikipedia Artikel

Wikipedia DE (CXCR1) [^]
Update: 29. April 2019