B Zell-Oberflächenantigen CD40

Kawabe T et al. (1994) The immune responses in CD40-deficient mice: impaired immunoglobulin class switching and germinal center formation.

Li F et al. (2011) Inhibitory Fcγ receptor engagement drives adjuvant and anti-tumor activities of agonistic CD40 antibodies.

Beatty GL et al. (2011) CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans.

Lanzi G et al. (2010) Different molecular behavior of CD40 mutants causing hyper-IgM syndrome.

Kraus ZJ et al. (2009) TRAF5 is a critical mediator of in vitro signals and in vivo functions of LMP1, the viral oncogenic mimic of CD40.

Matsuzawa A et al. (2008) Essential cytoplasmic translocation of a cytokine receptor-assembled signaling complex.

Peters AL et al. (2008) A novel polymorphism of the human CD40 receptor with enhanced function.

Pasare C et al. (2005) Control of B-cell responses by Toll-like receptors.

Harding SA et al. (2004) Upregulation of the CD40/CD40 ligand dyad and platelet-monocyte aggregation in cigarette smokers.

Trompouki E et al. (2003) CYLD is a deubiquitinating enzyme that negatively regulates NF-kappaB activation by TNFR family members.

Brodeur SR et al. (2003) C4b-binding protein (C4BP) activates B cells through the CD40 receptor.

Inwald DP et al. (2003) CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation.

Becker T et al. (2002) CD40, an extracellular receptor for binding and uptake of Hsp70-peptide complexes.

Schönbeck U et al. (2001) The CD40/CD154 receptor/ligand dyad.

Castigli E et al. (1994) CD40-deficient mice generated by recombination-activating gene-2-deficient blastocyst complementation.

Ferrari S et al. (2001) Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM.

Kutukculer N et al. (2003) Disseminated cryptosporidium infection in an infant with hyper-IgM syndrome caused by CD40 deficiency.

Mazzolari E et al. (2007) First report of successful stem cell transplantation in a child with CD40 deficiency.

Stamenkovic I et al. (1989) A B-lymphocyte activation molecule related to the nerve growth factor receptor and induced by cytokines in carcinomas.

Lafage-Pochitaloff M et al. (1994) Localization of the human CD40 gene to chromosome 20, bands q12-q13.2.

Asimakopoulos FA et al. (1996) The human CD40 gene lies within chromosome 20q deletions associated with myeloid malignancies.

Kato K et al. (1998) Gene transfer of CD40-ligand induces autologous immune recognition of chronic lymphocytic leukemia B cells.

Mach F et al. (1998) Reduction of atherosclerosis in mice by inhibition of CD40 signalling.

Tan J et al. (1999) Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.

van Kooten C et al. (2000) CD40-CD40 ligand.

Erickson LD et al. (2002) Short-circuiting long-lived humoral immunity by the heightened engagement of CD40.

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OMIM.ORG article

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