Molekulargenetisches Labor
Zentrum für Nephrologie und Stoffwechsel
Moldiag Erkrankungen Gene Support Kontakt

Psoriasis-Veranlagung 7

Die Veranlagung für Psoriasis lässt sich an verschiedenen Loci des Genoms festmachen. Der Typ 7 ist mit 1p verbunden.

Gliederung

Psoriasis
CARD14 assoziierte Psoriasis
Psoriasis 14
Psoriasis 15
Psoriasis-Veranlagung 1
Psoriasis-Veranlagung 10
Psoriasis-Veranlagung 11
Psoriasis-Veranlagung 12
Psoriasis-Veranlagung 13
Psoriasis-Veranlagung 3
Psoriasis-Veranlagung 4
Psoriasis-Veranlagung 5
Psoriasis-Veranlagung 6
Psoriasis-Veranlagung 7
Psoriasis-Veranlagung 8
Psoriasis-Veranlagung 9

Referenzen:

1.

Veal CD et al. (2001) Identification of a novel psoriasis susceptibility locus at 1p and evidence of epistasis between PSORS1 and candidate loci.

external link
2.

Parham C et al. (2002) A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R.

external link
3.

Kauffman CL et al. (2004) A phase I study evaluating the safety, pharmacokinetics, and clinical response of a human IL-12 p40 antibody in subjects with plaque psoriasis.

external link
4.

Cargill M et al. (2007) A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes.

external link
5.

Capon F et al. (2007) Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis.

external link
6.

Hüffmeier U et al. (2009) Genetic variants of the IL-23R pathway: association with psoriatic arthritis and psoriasis vulgaris, but no specific risk factor for arthritis.

external link
7.

Nair RP et al. (2009) Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways.

external link
Update: 14. August 2020
Copyright © 2005-2020 Zentrum für Nephrologie und Stoffwechsel, Dr. Mato Nagel
Albert-Schweitzer-Ring 32, D-02943 Weißwasser, Deutschland, Tel.: +49-3576-287922, Fax: +49-3576-287944
Seitenüberblick | Webmail | Haftungsausschluss | Datenschutz