Molekulargenetisches Labor
Zentrum für Nephrologie und Stoffwechsel
Moldiag Erkrankungen Gene Support Kontakt

Psoriasis-Veranlagung 4

Die Veranlagung für Psoriasis lässt sich an verschiedenen Loci des Genoms festmachen. Der Typ 4 ist mit 1q21 verbunden.

Gliederung

Psoriasis
CARD14 assoziierte Psoriasis
Psoriasis 14
Psoriasis 15
Psoriasis-Veranlagung 1
Psoriasis-Veranlagung 10
Psoriasis-Veranlagung 11
Psoriasis-Veranlagung 12
Psoriasis-Veranlagung 13
Psoriasis-Veranlagung 3
Psoriasis-Veranlagung 4
Psoriasis-Veranlagung 5
Psoriasis-Veranlagung 6
Psoriasis-Veranlagung 7
Psoriasis-Veranlagung 8
Psoriasis-Veranlagung 9

Referenzen:

1.

Capon F et al. (1999) Searching for psoriasis susceptibility genes in Italy: genome scan and evidence for a new locus on chromosome 1.

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2.

Capon F et al. (1999) Evidence for interaction between psoriasis-susceptibility loci on chromosomes 6p21 and 1q21.

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3.

Capon F et al. (2001) Fine mapping of the PSORS4 psoriasis susceptibility region on chromosome 1q21.

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4.

Giardina E et al. (2004) Characterization of the loricrin (LOR) gene as a positional candidate for the PSORS4 psoriasis susceptibility locus.

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5.

Zenz R et al. (2005) Psoriasis-like skin disease and arthritis caused by inducible epidermal deletion of Jun proteins.

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6.

Sun C et al. (2006) Peptidoglycan recognition proteins Pglyrp3 and Pglyrp4 are encoded from the epidermal differentiation complex and are candidate genes for the Psors4 locus on chromosome 1q21.

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7.

Giardina E et al. (2006) Co-localization of susceptibility loci for psoriasis (PSORS4) and atopic dermatitis (ATOD2) on human chromosome 1q21.

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8.

Chen H et al. (2009) Association of skin barrier genes within the PSORS4 locus is enriched in Singaporean Chinese with early-onset psoriasis.

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9.

de Cid R et al. (2009) Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis.

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10.

Zhang XJ et al. (2009) Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21.

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11.

Nemoto-Hasebe I et al. (2009) FLG mutation p.Lys4021X in the C-terminal imperfect filaggrin repeat in Japanese patients with atopic eczema.

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12.

Hu Z et al. (2012) Loss-of-function mutations in filaggrin gene associate with psoriasis vulgaris in Chinese population.

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Update: 14. August 2020
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