Bei genetischen Variationen an verschiedenen Loci wurde eine Assoziation mit systemischem Lupus erythematodes.
1. |
Wu H et al. (2007) Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus. ![]() |
3. |
Boteva L et al. (2012) Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations. ![]() |
4. |
Barreto M et al. (2004) Evidence for CTLA4 as a susceptibility gene for systemic lupus erythematosus. ![]() |
5. |
Lee YH et al. (2005) CTLA-4 polymorphisms and systemic lupus erythematosus (SLE): a meta-analysis. ![]() |
6. |
Napirei M et al. (2000) Features of systemic lupus erythematosus in Dnase1-deficient mice. ![]() |
7. |
Yasutomo K et al. (2001) Mutation of DNASE1 in people with systemic lupus erythematosus. ![]() |
8. |
Shin HD et al. (2004) Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients. ![]() |
9. |
Balada E et al. (2008) Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4+ T cells from patients with systemic lupus erythematosus. ![]() |
10. |
Sanghera DK et al. (1997) Identification of structural mutations in the fifth domain of apolipoprotein H (beta 2-glycoprotein I) which affect phospholipid binding. ![]() |
11. |
Linker-Israeli M et al. (1999) Association of IL-6 gene alleles with systemic lupus erythematosus (SLE) and with elevated IL-6 expression. ![]() |
12. |
Lee YH et al. (2006) Meta-analysis of TNF-alpha promoter -308 A/G polymorphism and SLE susceptibility. ![]() |
13. |
Hom G et al. (2008) Association of systemic lupus erythematosus with C8orf13-BLK and ITGAM-ITGAX. ![]() |
14. |
Kyogoku C et al. (2004) Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE. ![]() |
15. |
Orrú V et al. (2009) A loss-of-function variant of PTPN22 is associated with reduced risk of systemic lupus erythematosus. ![]() |
16. |
Kyogoku C et al. (2002) Fcgamma receptor gene polymorphisms in Japanese patients with systemic lupus erythematosus: contribution of FCGR2B to genetic susceptibility. ![]() |
18. |
McGaha TL et al. (2005) Restoration of tolerance in lupus by targeted inhibitory receptor expression. ![]() |
19. |
Blank MC et al. (2005) Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus. ![]() |
20. |
Floto RA et al. (2005) Loss of function of a lupus-associated FcgammaRIIb polymorphism through exclusion from lipid rafts. ![]() |
21. |
Willcocks LC et al. (2010) A defunctioning polymorphism in FCGR2B is associated with protection against malaria but susceptibility to systemic lupus erythematosus. ![]() |
22. |
Mueller M et al. (2013) Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus. ![]() |
23. |
Lee-Kirsch MA et al. (2007) Mutations in the gene encoding the 3'-5' DNA exonuclease TREX1 are associated with systemic lupus erythematosus. ![]() |
24. |
Yocum MW et al. () Monozygotic twins discordant for systemic lupus erythematosus. ![]() |
25. |
Beaucher WN et al. (1977) Familial lupus erythematosus. Antibodies to DNA in household dogs. ![]() |
26. |
Horn JR et al. () Mixed connective tissue disease in siblings. ![]() |
27. |
Miller KB et al. (1979) Familial abnormalities of suppressor-cell function in systemic lupus erythematosus. ![]() |
28. |
None (1979) Systemic lupus erythematosus, autoimmunity, sex and inheritance. ![]() |
29. |
Serdula MK et al. (1979) Frequency of systemic lupus erythematosus in different ethnic groups in Hawaii. ![]() |
30. |
Brustein D et al. (1977) Familial lupus erythematosus. ![]() |
31. |
Knight JG et al. (1978) Three genes for lupus nephritis in NZB x NZW mice. ![]() |
32. |
Arnett FC et al. (1976) Studies in familial systemic lupus erythematosus. ![]() |
33. |
DeHoratius RJ et al. (1975) Anti-nucleic acid antibodies in systemic lupus erythematosus patients and their families. Incidence and correlation with lymphocytotoxic antibodies. ![]() |
34. |
Block SR et al. (1975) Studies of twins with systemic lupus erythematosus. A review of the literature and presentation of 12 additional sets. ![]() |
35. |
Sturfelt G et al. (1990) Homozygous C4A deficiency in systemic lupus erythematosus: analysis of patients from a defined population. ![]() |
36. |
Stohl W et al. (1985) Systemic lupus erythematosus with deficiency of the T4 epitope on T helper/inducer cells. ![]() |
37. |
Sakane T et al. (1989) Familial occurrence of impaired interleukin-2 activity and increased peripheral blood B cells actively secreting immunoglobulins in systemic lupus erythematosus. ![]() |
38. |
Wong DW et al. (1988) Nonlinkage of the T cell receptor alpha, beta, and gamma genes to systemic lupus erythematosus in multiplex families. ![]() |
39. |
Levcovitz H et al. (1988) Segregation of lymphocyte low-molecular-weight DNA and antinuclear-antibodies in a family with systemic lupus erythematosus in first cousins. ![]() |
40. |
Green JR et al. (1986) The association of HLA-linked genes with systemic lupus erythematosus. ![]() |
41. |
Mackie IJ et al. (1987) Familial lupus anticoagulants. ![]() |
42. |
Baer AN et al. (1986) Further evidence for the lack of association between acetylator phenotype and systemic lupus erythematosus. ![]() |
43. |
Fronek Z et al. (1986) Systemic lupus erythematosus is not genetically linked to the beta chain of the T cell receptor. ![]() |
44. |
Halpern R et al. (1985) Familial systemic lupus erythematosus. Presence of a cross-reactive idiotype in healthy family members. ![]() |
45. |
Theofilopoulos AN et al. (1985) Murine models of systemic lupus erythematosus. ![]() |
46. |
None (1971) Lupus erythematosus panniculitis (profundus). ![]() |
47. |
None (1972) Family studies in systemic lupus erythematosus. I. A proband material from central eastern Norway. ![]() |
48. |
Siegel M et al. (1965) A comparative family study of rheumatoid arthritis and systemic lupus erythematosus. ![]() |
49. |
Lappat EJ et al. (1968) A familial study of procainamide-induced systemic lupus erythematosus. A question of pharmacogenetic polymorphism. ![]() |
50. |
None (1974) Systemic lupus erythematosus in the community. Incidence, prevalence, outcome, and first symptoms; the high prevalence in black women. ![]() |
51. |
Reed WB et al. (1972) Hereditary inflammatory vasculitis with persistent nodules. A genetically-determined new entity probably related to lupus erythematosus. ![]() |
52. |
Kohler PF et al. (1974) Hereditary angioedema and "familial" lupus erythematosus in identical twin boys. ![]() |
53. |
None (1973) Familial systemic lupus erythematosus. ![]() |
54. |
None (1972) Illness resembling lupus erythematosus in mothers of boys with chronic granulomatous disease. ![]() |
55. |
Larsen RA et al. (1972) Family studies in systemic lupus erythematosus (SLE). IX. Thyroid diseases and antibodies. ![]() |
56. |
Siegel M et al. () Epidemiologic studies on systemic lupus erythematosus. Comparative data for New York City and Jefferson County, Alabama, 1956-1965. ![]() |
57. |
Batchelor JR et al. (1980) Hydralazine-induced systemic lupus erythematosus: influence of HLA-DR and sex on susceptibility. ![]() |
58. |
Solomon G et al. (1983) Use of monoclonal antibodies to identify shared idiotypes on human antibodies to native DNA from patients with systemic lupus erythematosus. ![]() |
59. |
Steinberg AD et al. (1984) NIH conference. Systemic lupus erythematosus: insights from animal models. ![]() |
60. |
Hughes GR et al. (1983) Genetics of systemic lupus erythematosus. ![]() |
62. |
Diamond B et al. (1984) Somatic mutation of the T15 heavy chain gives rise to an antibody with autoantibody specificity. ![]() |
63. |
Reveille JD et al. (1983) Familial systemic lupus erythematosus: immunogenetic studies in eight families. ![]() |
64. |
Lahita RG et al. (1983) Familial systemic lupus erythematosus in males. ![]() |
65. |
Tan EM et al. (1982) The 1982 revised criteria for the classification of systemic lupus erythematosus. ![]() |
66. |
Reidenberg MM et al. (1980) Acetylator phenotype in idiopathic systemic lupus erythematosus. ![]() |
67. |
Exner T et al. (1980) Familial association of the lupus anticoagulant. ![]() |
68. |
Weinberg JB et al. (1980) Analysis of a large pedigree with elliptocytosis, multiple lipomatosis, and biological false-positive serological test for syphilis. ![]() |
69. |
Morel L et al. (1994) Polygenic control of susceptibility to murine systemic lupus erythematosus. ![]() |
70. |
Sibley JT et al. (1993) Familial systemic lupus erythematosus characterized by digital ischemia. ![]() |
71. |
None (1996) Systemic lupus erythematosus. ![]() |
72. |
Vyse TJ et al. (1996) Genetic analysis of autoimmune disease. ![]() |
73. |
None (1995) Genetics of systemic lupus erythematosus. ![]() |
74. |
Wu J et al. (1996) Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease. ![]() |
75. |
Vyse TJ et al. (1996) Genetic linkage of IgG autoantibody production in relation to lupus nephritis in New Zealand hybrid mice. ![]() |
76. |
García CO et al. (1996) Autoantibody profile in African-American patients with lupus nephritis. ![]() |
77. |
Lessard E et al. (1997) Role of CYP2D6 in the N-hydroxylation of procainamide. ![]() |
78. |
Elçioglu N et al. (1998) Maternal systemic lupus erythematosus and chondrodysplasia punctata in two sibs: phenocopy or coincidence? ![]() |
79. |
Austin-Ward E et al. (1998) Neonatal lupus syndrome: a case with chondrodysplasia punctata and other unusual manifestations. ![]() |
80. |
None (1998) Chondrodysplasia punctata and maternal systemic lupus erythematosus. ![]() |
81. |
Gaffney PM et al. (1998) A genome-wide search for susceptibility genes in human systemic lupus erythematosus sib-pair families. ![]() |
82. |
Shai R et al. (1999) Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families. ![]() |
83. |
Kelly TE et al. (1999) Chondrodysplasia punctata stemming from maternal lupus erythematosus. ![]() |
84. |
Mohan C et al. (1999) Genetic dissection of lupus pathogenesis: a recipe for nephrophilic autoantibodies. ![]() |
85. |
Lessard E et al. (1999) Involvement of CYP2D6 activity in the N-oxidation of procainamide in man. ![]() |
86. |
Lindqvist AK et al. (2000) A susceptibility locus for human systemic lupus erythematosus (hSLE1) on chromosome 2q. ![]() |
87. |
Gaffney PM et al. (2000) Genome screening in human systemic lupus erythematosus: results from a second Minnesota cohort and combined analyses of 187 sib-pair families. ![]() |
88. |
Gross JA et al. (2000) TACI and BCMA are receptors for a TNF homologue implicated in B-cell autoimmune disease. ![]() |
89. |
Gray-McGuire C et al. (2000) Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16-15.2. ![]() |
90. |
Zhang J et al. (2001) Cutting edge: a role for B lymphocyte stimulator in systemic lupus erythematosus. ![]() |
91. |
Solomou EE et al. (2001) Molecular basis of deficient IL-2 production in T cells from patients with systemic lupus erythematosus. ![]() |
92. |
DeGiorgio LA et al. (2001) A subset of lupus anti-DNA antibodies cross-reacts with the NR2 glutamate receptor in systemic lupus erythematosus. ![]() |
93. |
Blanco P et al. (2001) Induction of dendritic cell differentiation by IFN-alpha in systemic lupus erythematosus. ![]() |
94. |
Stein CM et al. (2002) Increased prevalence of renal disease in systemic lupus erythematosus families with affected male relatives. ![]() |
95. |
Leadbetter EA et al. (2002) Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. ![]() |
96. |
Graham RR et al. (2002) Visualizing human leukocyte antigen class II risk haplotypes in human systemic lupus erythematosus. ![]() |
97. |
Quintero-Del-Rio AI et al. (2002) The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3). ![]() |
98. |
Kelly JA et al. (2002) The genetics of systemic lupus erythematosus: putting the pieces together. ![]() |
99. |
Johanneson B et al. (2002) A major susceptibility locus for systemic lupus erythemathosus maps to chromosome 1q31. ![]() |
100. |
Scofield RH et al. (2003) Thrombocytopenia identifies a severe familial phenotype of systemic lupus erythematosus and reveals genetic linkages at 1q22 and 11p13. ![]() |
101. |
Prokunina L et al. (2002) A regulatory polymorphism in PDCD1 is associated with susceptibility to systemic lupus erythematosus in humans. ![]() |
102. |
Sun Y et al. (2002) Costimulatory molecule-targeted antibody therapy of a spontaneous autoimmune disease. ![]() |
103. |
Molokhia M et al. (2003) Relation of risk of systemic lupus erythematosus to west African admixture in a Caribbean population. ![]() |
104. |
Baechler EC et al. (2003) Interferon-inducible gene expression signature in peripheral blood cells of patients with severe lupus. ![]() |
105. |
Nakamura K et al. (2003) Genetic dissection of anxiety in autoimmune disease. ![]() |
106. |
None (1964) ANTINUCLEAR ANTIBODIES IN FAMILIES OF PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS. ![]() |
107. |
Kamat SS et al. (2003) Triplets with systemic lupus erythematosus. ![]() |
108. |
Russell AI et al. (2004) Polymorphism at the C-reactive protein locus influences gene expression and predisposes to systemic lupus erythematosus. ![]() |
109. |
Li N et al. (2004) Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus. ![]() |
110. |
Xu L et al. (2004) Human lupus T cells resist inactivation and escape death by upregulating COX-2. ![]() |
111. |
Tournoy J et al. (2004) Partial loss of presenilins causes seborrheic keratosis and autoimmune disease in mice. ![]() |
112. |
Kozlowski K et al. (2004) Chondrodysplasia punctata in siblings and maternal lupus erythematosus. ![]() |
113. |
Sigurdsson S et al. (2005) Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. ![]() |
114. |
Tao D et al. (2005) CD226 expression deficiency causes high sensitivity to apoptosis in NK T cells from patients with systemic lupus erythematosus. ![]() |
115. |
Barber DF et al. (2005) PI3Kgamma inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus. ![]() |
116. |
Xing C et al. (2005) Genetic linkage of systemic lupus erythematosus to 13q32 in African American families with affected male members. ![]() |
117. |
Lee YH et al. (2005) Systemic lupus erythematosus susceptibility loci defined by genome scan meta-analysis. ![]() |
118. |
Huerta PT et al. (2006) Immunity and behavior: antibodies alter emotion. ![]() |
119. |
Aitman TJ et al. (2006) Copy number polymorphism in Fcgr3 predisposes to glomerulonephritis in rats and humans. ![]() |
120. |
Graham RR et al. (2006) A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosus. ![]() |
121. |
Kowal C et al. (2006) Human lupus autoantibodies against NMDA receptors mediate cognitive impairment. ![]() |
122. |
Fanciulli M et al. (2007) FCGR3B copy number variation is associated with susceptibility to systemic, but not organ-specific, autoimmunity. ![]() |
123. |
Remmers EF et al. (2007) STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosus. ![]() |
124. |
Kamatani Y et al. (2008) Identification of a significant association of a single nucleotide polymorphism in TNXB with systemic lupus erythematosus in a Japanese population. ![]() |
125. |
Cunninghame Graham DS et al. (2008) Polymorphism at the TNF superfamily gene TNFSF4 confers susceptibility to systemic lupus erythematosus. ![]() |
126. |
et al. (2008) Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci. ![]() |
127. |
Kozyrev SV et al. (2008) Functional variants in the B-cell gene BANK1 are associated with systemic lupus erythematosus. ![]() |
128. |
Nath SK et al. (2008) A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. ![]() |
129. |
Oishi T et al. (2008) A functional SNP in the NKX2.5-binding site of ITPR3 promoter is associated with susceptibility to systemic lupus erythematosus in Japanese population. ![]() |
130. |
Willcocks LC et al. (2008) Copy number of FCGR3B, which is associated with systemic lupus erythematosus, correlates with protein expression and immune complex uptake. ![]() |
131. |
Graham RR et al. (2008) Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus. ![]() |
132. |
Musone SL et al. (2008) Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosus. ![]() |
133. |
Sthoeger ZM et al. (2009) High alpha-defensin levels in patients with systemic lupus erythematosus. ![]() |
134. |
Sánchez E et al. (2009) Identification of a new putative functional IL18 gene variant through an association study in systemic lupus erythematosus. ![]() |
135. |
Han JW et al. (2009) Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus. ![]() |
136. |
Gateva V et al. (2009) A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus. ![]() |
137. |
Myouzen K et al. (2010) Regulatory polymorphisms in EGR2 are associated with susceptibility to systemic lupus erythematosus. ![]() |
138. |
Niederer HA et al. (2010) Copy number, linkage disequilibrium and disease association in the FCGR locus. ![]() |
139. |
Guiducci C et al. (2010) TLR recognition of self nucleic acids hampers glucocorticoid activity in lupus. ![]() |
140. |
Olsson LM et al. (2012) Copy number variation of the gene NCF1 is associated with rheumatoid arthritis. ![]() |
141. |
Manjarrez-Orduño N et al. (2012) CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation. ![]() |
142. |
Kshirsagar S et al. (2014) Akt-dependent enhanced migratory capacity of Th17 cells from children with lupus nephritis. ![]() |
143. |
Talaei N et al. (2015) Identification of the SLAM Adapter Molecule EAT-2 as a Lupus-Susceptibility Gene That Acts through Impaired Negative Regulation of Dendritic Cell Signaling. ![]() |
144. |
Zhao J et al. (2017) A missense variant in NCF1 is associated with susceptibility to multiple autoimmune diseases. ![]() |
145. |
Bialas AR et al. (2017) Microglia-dependent synapse loss in type I interferon-mediated lupus. ![]() |
146. |
Wikipedia Artikel Wikipedia DE (Lupus_erythematodes)![]() |