Molekulargenetisches Labor
Zentrum für Nephrologie und Stoffwechsel

Neigung zu Kaposi-Sarkomen

Die Neigung zu Kaposi-Sarkomen wird durch autosomal dominante Keimbahnmutationen im IL6-Gen beeinflusst.

Gliederung

Erbliche Tumorerkrankungen
Hereditäre Nierentumoren
Hereditäre maligne Bluterkrankungen
Infantiles kapilläres Hämangiom
Multiple selbsheilende palmoplantare Karzinome
Neigung zu Kaposi-Sarkomen
IL6
Neurofibromatose

Referenzen:

1.

Foster CB et. al. (2000) An IL6 promoter polymorphism is associated with a lifetime risk of development of Kaposi sarcoma in men infected with human immunodeficiency virus.

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2.

Chow D et. al. (2001) Structure of an extracellular gp130 cytokine receptor signaling complex.

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3.

Suthaus J et. al. (2012) HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice.

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4.

Finlay AY et. al. (1979) Familial Kaposi's sarcoma.

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5.

Gottlieb MS et. al. (1981) Pneumocystis carinii pneumonia and mucosal candidiasis in previously healthy homosexual men: evidence of a new acquired cellular immunodeficiency.

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6.

None (1981) Opportunistic infections and Kaposi's sarcoma in homosexual men.

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7.

Masur H et. al. (1981) An outbreak of community-acquired Pneumocystis carinii pneumonia: initial manifestation of cellular immune dysfunction.

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8.

DiGiovanna JJ et. al. (1981) Kaposi's sarcoma. Retrospective study of 90 cases with particular emphasis on the familial occurrence, ethnic background and prevalence of other diseases.

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9.

Chang Y et. al. (1994) Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma.

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10.

Kedes DH et. al. (1996) The seroepidemiology of human herpesvirus 8 (Kaposi's sarcoma-associated herpesvirus): distribution of infection in KS risk groups and evidence for sexual transmission.

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11.

Gao SJ et. al. (1996) KSHV antibodies among Americans, Italians and Ugandans with and without Kaposi's sarcoma.

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12.

Rabkin CS et. al. (1997) Monoclonal origin of multicentric Kaposi's sarcoma lesions.

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13.

Hjalgrim H et. al. (1998) High incidence of classical Kaposi's sarcoma in Iceland and the Faroe Islands.

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14.

None (2003) Kaposi's sarcoma-associated herpesvirus--the high cost of viral survival.

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15.

Cool CD et. al. (2003) Expression of human herpesvirus 8 in primary pulmonary hypertension.

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16.

None (1960) Kaposi's sarcoma in a father and son.

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17.

Guttman-Yassky E et. al. (2003) Epidemiology of classic Kaposi's sarcoma in the Israeli Jewish population between 1960 and 1998.

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18.

Hong YK et. al. (2004) Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma-associated herpesvirus.

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19.

Wang HW et. al. (2004) Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma.

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20.

Grange PA et. al. (2005) Salivary lactoferrin is recognized by the human herpesvirus-8.

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21.

Grange PA et. al. (2012) Cloning a human saliva-derived peptide for preventing KSHV transmission.

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Update: 8. Mai 2019