Molekulargenetisches Labor
Zentrum für Nephrologie und Stoffwechsel
Moldiag Erkrankungen Gene Support Kontakt

Psoriasis 02

Psoriasis 2 ist eine autosomal dominante systemische autoinflammatorische Erkrankung mir vorwiegend kutaner Manifestation, die durch Mutationen im CARD14-Gen hervorgerufen wird.

Gliederung

CARD14 assoziierte Psoriasis
Pityriasis rubra pilaris
Psoriasis 02
CARD14

Referenzen:

1.

Helms C et. al. (2003) A putative RUNX1 binding site variant between SLC9A3R1 and NAT9 is associated with susceptibility to psoriasis.

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2.

Nair RP et al. (1997) Evidence for two psoriasis susceptibility loci (HLA and 17q) and two novel candidate regions (16q and 20p) by genome-wide scan.

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3.

Tomfohrde J et. al. (1994) Gene for familial psoriasis susceptibility mapped to the distal end of human chromosome 17q.

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4.

Hwu WL et. al. (2005) Mapping of psoriasis to 17q terminus.

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5.

Jordan CT et. al. (2012) PSORS2 is due to mutations in CARD14.

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6.

Jordan CT et al. (2012) Rare and common variants in CARD14, encoding an epidermal regulator of NF-kappaB, in psoriasis.

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7.

Nair RP et. al. () Scanning chromosome 17 for psoriasis susceptibility: lack of evidence for a distal 17q locus.

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8.

Matthews D et. al. (1995) Confirmation of genetic heterogeneity in familial psoriasis.

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9.

Enlund F et al. (1999) Analysis of three suggested psoriasis susceptibility loci in a large Swedish set of families: confirmation of linkage to chromosome 6p (HLA region), and to 17q, but not to 4q.

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10.

Speckman RA et. al. (2003) Novel immunoglobulin superfamily gene cluster, mapping to a region of human chromosome 17q25, linked to psoriasis susceptibility.

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11.

Capon F et. al. (2004) Genetic analysis of PSORS2 markers in a UK dataset supports the association between RAPTOR SNPs and familial psoriasis.

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12.

Stuart P et. al. (2006) Analysis of RUNX1 binding site and RAPTOR polymorphisms in psoriasis: no evidence for association despite adequate power and evidence for linkage.

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13.

Giardina E et. al. (2006) PSORS2 markers are not associated with psoriatic arthritis in the Italian population.

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Update: 14. August 2020
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