Molekulargenetische Diagnostik
Praxis Dr. Mato Nagel

Migräne

Migräne ist ein vaskulärer periodisch auftretender Kopfschmerz, der eine familäre Häufung zeigen kann verschiedene genetische Faktoren die eine Neigung zur Migräne beeinflussen können sind identifiziert worden.

Gliederung

Erbliche Nervenerkrankungen
Alzheimer Erkrankung
Arts-Syndrom
Autismus
Autosomal dominante zerebelläre Ataxie mit Schwerhörigkeit und Narkolepsie
Autosomal rezessive spastische Paraplegie 44
Brunner-Syndrom
Charcot-Marie-Tooth-Hoffmann-Krankheit
Erbliche Erkrankungen der Muskeln
Gliom-Neigung
Hereditäre benigne Chorea
Hereditäre distale Motorneuronen-Neuropathie Typ 5A
Hereditäre sensorisch-autonome Neuropathie Typ 2A
Hereditäre sensorische Neuropathie Typ 1E
Hirnmalformation mit Urogenitaldefekten
Hypokalämische periodische Paralyse 1
Hypomyelinisierte Leukodystrophy 2
Idiopathische Kalzifikation der Basalganglien 1
Kongenitale Schmerzunempfindlichkeit mit Anhidrose
Migräne
TNF
Nemaline-Myopathy 5
Neonatale Enzephalopathie mit Mikrozephalie
Porenzephalie
Rett-Syndrom
Spastische Paraplegie 17 mit Amyotrophie der Hände und Füße
Syndrom der Intelligenzminderung mit stark verzögerter Sprachentwicklung und milden Dysmorphien
Vaskuläre Demenz
X-chromosomale syndromale mentale Retardierung 13
Zerebrale Mikroangiopathie mit Blutung

Referenzen:

1.

None (1977) Migraine in twins.

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2.

Goadsby PJ et. al. (1990) Vasoactive peptide release in the extracerebral circulation of humans during migraine headache.

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3.

Stewart WF et. al. (1992) Prevalence of migraine headache in the United States. Relation to age, income, race, and other sociodemographic factors.

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4.

Hiner BC et. al. (1986) Antimigraine drug interactions with 5-hydroxytryptamine1A receptors.

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5.

Devoto M et. al. (1986) Segregation analysis of migraine in 128 families.

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6.

None (1985) Migraine and muscle contraction headaches: a continuum.

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7.

Glover V et. al. (1983) Biochemical predisposition to dietary migraine: the role of phenolsulphotransferase.

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8.

Russell MB et. al. (1993) Familial occurrence of migraine without aura and migraine with aura.

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9.

Russell MB et. al. (1995) Inheritance of migraine investigated by complex segregation analysis.

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10.

Stewart WF et. al. (1996) Variation in migraine prevalence by race.

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11.

Ulrich V et. al. (1997) Analysis of 31 families with an apparently autosomal-dominant transmission of migraine with aura in the nuclear family.

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12.

Ulrich V et. al. (1999) Evidence of a genetic factor in migraine with aura: a population-based Danish twin study.

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13.

Gervil M et. al. (1999) Migraine without aura: a population-based twin study.

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14.

Kowa H et. al. (2000) The homozygous C677T mutation in the methylenetetrahydrofolate reductase gene is a genetic risk factor for migraine.

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15.

Wessman M et. al. (2002) A susceptibility locus for migraine with aura, on chromosome 4q24.

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16.

Reuter U et. al. (2002) Nuclear factor-kappaB as a molecular target for migraine therapy.

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17.

Lassen LH et. al. (2002) CGRP may play a causative role in migraine.

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18.

GOODELL H et. al. (1954) Familiar occurrence of migraine headache: a study of heredity.

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19.

None (1965) MIGRAINE AND HEREDITY.

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20.

Björnsson A et. al. (2003) Localization of a gene for migraine without aura to chromosome 4q21.

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21.

Olesen J et. al. (2004) Calcitonin gene-related peptide receptor antagonist BIBN 4096 BS for the acute treatment of migraine.

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22.

Oterino A et. al. (2004) MTHFR T677 homozygosis influences the presence of aura in migraineurs.

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23.

Scher AI et. al. (2006) Migraine and MTHFR C677T genotype in a population-based sample.

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24.

Ludvigsson P et. al. (2006) Migraine with aura is a risk factor for unprovoked seizures in children.

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25.

Stewart WF et. al. (2006) Familial risk of migraine: variation by proband age at onset and headache severity.

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26.

Anttila V et. al. (2006) Trait components provide tools to dissect the genetic susceptibility of migraine.

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27.

Stam AH et. al. (2010) Shared genetic factors in migraine and depression: evidence from a genetic isolate.

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28.

Karatas H et. al. (2013) Spreading depression triggers headache by activating neuronal Panx1 channels.

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29.

Anttila V et. al. (2013) Genome-wide meta-analysis identifies new susceptibility loci for migraine.

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Update: 26. September 2018

 

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