Osteomyelofibrose ist eine Knochemarkerkrankung bei der es zu einer übermäßigen Fibrosierung des Knochenmarkes kommt. Das Knochenmark wird von fibrotischem Narbengewebe verdrängt. Die Erkrankung kann durch somatische Mutationen im JAK2-Gen hervorgerufen werden.
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Orphanet article Orphanet ID 824![]() |
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OMIM.ORG article Omim 254450![]() |
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Wikipedia Artikel Wikipedia DE (Osteomyelofibrose)![]() |