TRH-Mangel
Der TRH-Mangel ist eine autosomal rezessive Erkrankung, die durch Mutationen im TRH-Gen ausgelöst wird.
Gliederung
Zentrale Hypothyreose
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Generalisierte TRH-Resistenz
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TRH-Mangel
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TRH
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Zentrale Hypothyreose und Makroorchidie
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Referenzen:
| 1. |
Mitnick M et al. (1972) Enzymatic synthesis of thyrotropin releasing hormone (TRH) by hypothalamic "TRH synthetase". [^] |
| 2. |
Foresti V et al. (1985) Central hypothyroidism: isolated thyrotropin-releasing hormone deficiency or resistance of pituitary thyrotropes? [^] |
| 3. |
Katakami H et al. (1984) Hypothalamic hypothyroidism due to isolated thyrotropin-releasing hormone (TRH) deficiency. [^] |
| 4. |
Niimi H et al. (1982) Congenital isolated thyrotrophin releasing hormone deficiency. [^] |
| 5. |
OMIM.ORG article Omim 275120 [^] |
Update: 10. Mai 2019
