Das hereditäre nicht-medulläres Schilddrüsenkarzinom 4 ist eine autosomal dominante Erkrankung, die durch Mutationen im FOXE1-Gen ausgelöst wird.
1. |
Pereira JS et al. (2015) Identification of a novel germline FOXE1 variant in patients with familial non-medullary thyroid carcinoma (FNMTC). |
2. |
Denny JC et al. (2011) Variants near FOXE1 are associated with hypothyroidism and other thyroid conditions: using electronic medical records for genome- and phenome-wide studies. |
3. |
Gudmundsson J et al. (2009) Common variants on 9q22.33 and 14q13.3 predispose to thyroid cancer in European populations. |
4. |
Takahashi M et al. (2010) The FOXE1 locus is a major genetic determinant for radiation-related thyroid carcinoma in Chernobyl. |
5. |
OMIM.ORG article Omim 616534 |