Molekulargenetische Diagnostik
Praxis Dr. Mato Nagel

Neigung zu autoimmunbedingten Schilddrüsenerkrankungen 3

Der Typ 3 der Neigung zu autoimmunbedingten Schilddrüsenerkrankungen wird durch Polymorphismen im ZFAT- und TG-Gen verursacht.

Gliederung

Neigung zu autoimmunbedingten Schilddrüsenerkrankungen
Basedow-Krankheit
Neigung zu autoimmunbedingten Schilddrüsenerkrankungen 1
Neigung zu autoimmunbedingten Schilddrüsenerkrankungen 2
Neigung zu autoimmunbedingten Schilddrüsenerkrankungen 3
TG
ZFAT
Neigung zu autoimmunbedingten Schilddrüsenerkrankungen 4
Neigung zu autoimmunbedingten Schilddrüsenerkrankungen 5

Referenzen:

1.

Ban Y et. al. (2003) Amino acid substitutions in the thyroglobulin gene are associated with susceptibility to human and murine autoimmune thyroid disease.

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2.

Collins JE et. al. (2004) Common allelic variants of exons 10, 12, and 33 of the thyroglobulin gene are not associated with autoimmune thyroid disease in the United Kingdom.

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3.

Sakai K et. al. (2001) Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q33 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese.

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4.

Shirasawa S et. al. (2004) SNPs in the promoter of a B cell-specific antisense transcript, SAS-ZFAT, determine susceptibility to autoimmune thyroid disease.

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5.

Tomer Y et. al. (2003) Common and unique susceptibility loci in Graves and Hashimoto diseases: results of whole-genome screening in a data set of 102 multiplex families.

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6.

Collins JE et. al. (2003) Association of a rare thyroglobulin gene microsatellite variant with autoimmune thyroid disease.

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7.

Tomer Y et. al. (1999) Mapping the major susceptibility loci for familial Graves' and Hashimoto's diseases: evidence for genetic heterogeneity and gene interactions.

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8.

Tomer Y et. al. (2002) Thyroglobulin is a thyroid specific gene for the familial autoimmune thyroid diseases.

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