Malformationen der Rechts-Links-Achse
Malformationen der Rechts-Links-Achse finden sich bei dominanten Mutationen des LEFTY2-Gens.
Gliederung
Referenzen:
1. |
Meno C et al. (1996) Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. [^] |
2. |
Kothapalli R et al. (1997) Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding. [^] |
3. |
Meno C et al. (1997) Two closely-related left-right asymmetrically expressed genes, lefty-1 and lefty-2: their distinct expression domains, chromosomal linkage and direct neuralizing activity in Xenopus embryos. [^] |
4. |
Kosaki K et al. (1999) Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development. [^] |
5. |
Meno C et al. (1999) Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. [^] |
6. |
Burdine RD et al. (2000) Conserved and divergent mechanisms in left-right axis formation. [^] |
7. |
Tabibzadeh S et al. (2000) Dysregulated expression of ebaf, a novel molecular defect in the endometria of patients with infertility. [^] |
8. |
Meno C et al. (2001) Diffusion of nodal signaling activity in the absence of the feedback inhibitor Lefty2. [^] |
9. |
OMIM.ORG article Omim 601877 [^] |