Malformationen der Rechts-Links-Achse finden sich bei dominanten Mutationen des LEFTY2-Gens.
1. |
Meno C et al. (1996) Left-right asymmetric expression of the TGF beta-family member lefty in mouse embryos. |
2. |
Kothapalli R et al. (1997) Detection of ebaf, a novel human gene of the transforming growth factor beta superfamily association of gene expression with endometrial bleeding. |
4. |
Kosaki K et al. (1999) Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development. |
5. |
Meno C et al. (1999) Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation. |
6. |
Burdine RD et al. (2000) Conserved and divergent mechanisms in left-right axis formation. |
7. |
Tabibzadeh S et al. (2000) Dysregulated expression of ebaf, a novel molecular defect in the endometria of patients with infertility. |
8. |
Meno C et al. (2001) Diffusion of nodal signaling activity in the absence of the feedback inhibitor Lefty2. |
9. |
OMIM.ORG article Omim 601877 |