Der Typ 11 der Lippen-Kiefer-Gaumenspalte wird durch Mutationen im BMP4-Gen hervorgerufen.
1. |
Liu W et al. (2005) Distinct functions for Bmp signaling in lip and palate fusion in mice. |
2. |
Suzuki S et al. (2009) Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip. |
3. |
Castilla EE et al. (1995) Congenital healed cleft lip. |
4. |
Neiswanger K et al. (2007) Orbicularis oris muscle defects as an expanded phenotypic feature in nonsyndromic cleft lip with or without cleft palate. |
5. |
OMIM.ORG article Omim 600625 |