Genetischer BMI-Faktor 14
Genetische Veränderungen im FTO-Gen führen in rezesiver Form zu Übergewicht.
Gliederung
Referenzen:
1. |
Loos RJ et. al. (2008) Common variants near MC4R are associated with fat mass, weight and risk of obesity. [^] |
2. |
Willer CJ et. al. (2009) Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. [^] |
3. |
Hardy R et. al. (2010) Life course variations in the associations between FTO and MC4R gene variants and body size. [^] |
4. |
Frayling TM et. al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. [^] |
5. |
Dina C et. al. (2007) Variation in FTO contributes to childhood obesity and severe adult obesity. [^] |
6. |
Meyre D et. al. (2009) Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. [^] |
7. |
Claussnitzer M et. al. (2015) FTO Obesity Variant Circuitry and Adipocyte Browning in Humans. [^] |
8. |
Kilpeläinen TO et. al. (2011) Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. [^] |
9. |
Renström F et. al. (2009) Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden. [^] |
10. |
Ohashi J et. al. (2007) FTO polymorphisms in oceanic populations. [^] |
11. |
Wardle J et. al. (2008) Obesity associated genetic variation in FTO is associated with diminished satiety. [^] |
12. |
Cecil JE et. al. (2008) An obesity-associated FTO gene variant and increased energy intake in children. [^] |
13. |
Jonsson A et. al. (2009) Obesity, FTO gene variant, and energy intake in children. [^] |
14. |
Kent P et. al. (2009) Case 3-2009: a 9-month-old boy with seizures. [^] |
15. |
Ho AJ et. al. (2010) A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. [^] |
16. |
Yang J et. al. (2012) FTO genotype is associated with phenotypic variability of body mass index. [^] |