Genetische Veränderungen im FTO-Gen führen in rezesiver Form zu Übergewicht.
1. |
Willer CJ et al. (2009) Six new loci associated with body mass index highlight a neuronal influence on body weight regulation. |
2. |
Yang J et al. (2012) FTO genotype is associated with phenotypic variability of body mass index. |
3. |
Ho AJ et al. (2010) A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. |
4. |
Kent P et al. (2009) Case 3-2009: a 9-month-old boy with seizures. |
5. |
Jonsson A et al. (2009) Obesity, FTO gene variant, and energy intake in children. |
6. |
Cecil JE et al. (2008) An obesity-associated FTO gene variant and increased energy intake in children. |
7. |
Wardle J et al. (2008) Obesity associated genetic variation in FTO is associated with diminished satiety. |
8. |
Ohashi J et al. (2007) FTO polymorphisms in oceanic populations. |
9. |
Renström F et al. (2009) Replication and extension of genome-wide association study results for obesity in 4923 adults from northern Sweden. |
10. |
Kilpeläinen TO et al. (2011) Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile. |
11. |
Claussnitzer M et al. (2015) FTO Obesity Variant Circuitry and Adipocyte Browning in Humans. |
12. |
Dina C et al. (2007) Variation in FTO contributes to childhood obesity and severe adult obesity. |
13. |
Frayling TM et al. (2007) A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity. |
14. |
Meyre D et al. (2009) Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations. |
15. |
Hardy R et al. (2010) Life course variations in the associations between FTO and MC4R gene variants and body size. |
16. |
Loos RJ et al. (2008) Common variants near MC4R are associated with fat mass, weight and risk of obesity. |
17. |
OMIM.ORG article Omim 612460 |