Molekulargenetisches Labor
Zentrum für Nephrologie und Stoffwechsel
Moldiag Erkrankungen Gene Support Kontakt

Weitwinkelglaukom 1E

Das Weitwinkelglaukom 1E ist eine autosomal dominante Erkrankung, die durch Mutationen im OPTN-Gen ausgelöst wird.

Gliederung

Weitwinkelglaukom 1
Weitwinkelglaukom 1A
Weitwinkelglaukom 1B
Weitwinkelglaukom 1C
Weitwinkelglaukom 1D
Weitwinkelglaukom 1E
OPTN
Weitwinkelglaukom 1F
Weitwinkelglaukom 1G
Weitwinkelglaukom 1H
Weitwinkelglaukom 1I
Weitwinkelglaukom 1J
Weitwinkelglaukom 1K
Weitwinkelglaukom 1L
Weitwinkelglaukom 1M
Weitwinkelglaukom 1N
Weitwinkelglaukom 1O
Weitwinkelglaukom 1P

Referenzen:

1.

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2.

Harwerth RS et al. (1999) Ganglion cell losses underlying visual field defects from experimental glaucoma.

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3.

Leung YF et al. (2000) Absence of trabecular meshwork-inducible stretch response (TISR)/oculomedin gene and proximal promoter mutation in primary open angle glaucoma patients.

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4.

Yang J et al. (2001) T cell subsets and sIL-2R/IL-2 levels in patients with glaucoma.

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5.

Nemesure B et al. (2003) A genome-wide scan for primary open-angle glaucoma (POAG): the Barbados Family Study of Open-Angle Glaucoma.

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6.

Klein BE et al. (2004) Heritability of risk factors for primary open-angle glaucoma: the Beaver Dam Eye Study.

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7.

Chauhan BC et al. (2004) Model of endothelin-1-induced chronic optic neuropathy in rat.

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8.

Gottanka J et al. (2004) Effects of TGF-beta2 in perfused human eyes.

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9.

Ferreira SM et al. (2004) Oxidative stress markers in aqueous humor of glaucoma patients.

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10.

Tanito M et al. (2004) Reduction of posterior pole retinal thickness in glaucoma detected using the Retinal Thickness Analyzer.

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11.

Sarfarazi M et al. (1998) Localization of the fourth locus (GLC1E) for adult-onset primary open-angle glaucoma to the 10p15-p14 region.

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12.

Wang L et al. (2006) Endothelin B receptor in human glaucoma and experimentally induced optic nerve damage.

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13.

Xu L et al. (2007) High myopia and glaucoma susceptibility the Beijing Eye Study.

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14.

Polak K et al. (2007) Altered nitric oxide system in patients with open-angle glaucoma.

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15.

Hewitt AW et al. (2007) Heritable features of the optic disc: a novel twin method for determining genetic significance.

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16.

Johnson EC et al. (2007) Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model.

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17.

Xue W et al. (2007) Presence of an established calcification marker in trabecular meshwork tissue of glaucoma donors.

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18.

Bahler CK et al. (2008) Prostaglandins increase trabecular meshwork outflow facility in cultured human anterior segments.

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19.

Burdon KP et al. (2011) Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1.

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20.

Borrás T et al. (2015) Prevention of nocturnal elevation of intraocular pressure by gene transfer of dominant-negative RhoA in rats.

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21.

None (1997) Recent advances in molecular genetics of glaucomas.

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22.

Wordinger RJ et al. (2007) Effects of TGF-beta2, BMP-4, and gremlin in the trabecular meshwork: implications for glaucoma.

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23.

Rezaie T et al. (2002) Adult-onset primary open-angle glaucoma caused by mutations in optineurin.

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24.

Chalasani ML et al. (2007) A glaucoma-associated mutant of optineurin selectively induces death of retinal ganglion cells which is inhibited by antioxidants.

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25.

Wiggs JL et al. (2000) Genome-wide scan for adult onset primary open angle glaucoma.

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26.

Wiggs JL et al. (1996) The distinction between juvenile and adult-onset primary open-angle glaucoma.

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27.

None (1965) THE INHERITANCE OF GLAUCOMA. A PEDIGREE OF FAMILIAL GLAUCOMA.

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28.

Wiggs JL et al. (2004) A genomewide scan identifies novel early-onset primary open-angle glaucoma loci on 9q22 and 20p12.

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29.

None (1978) Current concepts in ophthalmology: the glaucomas.

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30.

Southren AL et al. (1985) Genetic defect in cortisol metabolism in primary open angle glaucoma.

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31.

Schwartz JT et al. (1972) Twin heritability study of the effect of corticosteroids on intraocular pressure.

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32.

Armaly MF et al. (1968) Ocular pressure and aqueous outflow facility in siblings.

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33.

None (1966) The heritable nature of dexamethasone-induced ocular hypertension.

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34.

Coulehan JL et al. (1980) Racial differences in intraocular tension and glaucoma surgery.

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35.

Quigley HA et al. (1994) Risk factors for the development of glaucomatous visual field loss in ocular hypertension.

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36.

None (1993) Open-angle glaucoma.

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37.

Quigley HA et al. (1997) Models of open-angle glaucoma prevalence and incidence in the United States.

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38.

None (1997) Molecular genetics of the glaucomas: mapping of the first five "GLC" loci.

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39.

Allingham RR et al. () Adult-onset primary open angle glaucoma does not localize to chromosome 2cen-q13 in North American families.

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40.

OMIM.ORG article

Omim 137760 external link
Update: 14. August 2020
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