Molekulargenetisches Labor
Zentrum für Nephrologie und Stoffwechsel
Moldiag Erkrankungen Gene Support Kontakt

Mannose-Bindungsprotein-Mangel

Der Mangel an Mannose-Bindungsprotein, der durch Mutationen im MBL2-Gen hervorgerufen wird besitzt selbst keinen Krankheitswert. Es wird jedoch eine häufiges Zusammentreffen dieses Mangel und chronisch entzündlichen Erkrankungen und Gestationsdiabetes festgestellt.

Epidemiologie

Der Mannose-Bindungsprotein-Mangel wird bei 5% der Kaukasier und sogar bei 10% der Afrikaner beobachtet.

Diagnosestellung

Eine Proteinkonzentration von weniger als 100 ng/ml wird als Mangel betrachtet.

Gliederung

Gestationsdiabetes
MODY Diabetes
Mannose-Bindungsprotein-Mangel
MBL2
Mitchell-Riley-Syndrom
Partielle Lipodystrophie
Suszeptibilität für Typ 1 Diabetes 01
TRPM6

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