Der Panhypopituitarismus, der nun als kombinierter Hyophysenhormonmangel vom Typ 2 eingeordnet wurde, ist eine autosomal rezessive Erkrankung, die durch Mutationen im PROP1-Gen hervorgerufen wird. Klinisch stehen die Symptome der fehlenden Hypophysenhormone im Vordergrund. Dabei sind insbesondere der Kleinwuchs und der Hypogonadismus auffällig.
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OMIM.ORG article Omim 262600![]() |
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Orphanet article Orphanet ID 90695![]() |
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Wikipedia Artikel Wikipedia DE (Panhypopituitarismus)![]() |