Defekte bei Komplementfaktoren des terminalen Abschnittes der Koplmemetaktivierung sind insbesondere durch Störungen der Infektabwehr gekennzeichnet. Dies betrifft besonders die Abwehr von Neisserien-Erkrankungen. Derartige Defekte betreffen die Faktoren C5-C9.
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OMIM.ORG article Omim 609536 |