Milroy-ähnliches primäres Lymphödem ist eine autosomal dominante Erkrankung die durch trunkierende Mutationen im VEGFC-Gen hervorgerufen wird.
2. |
Villefranc JA et al. (2013) A truncation allele in vascular endothelial growth factor c reveals distinct modes of signaling during lymphatic and vascular development. ![]() |
3. |
Rezaie T et al. (2008) Primary non-syndromic lymphoedema (Meige disease) is not caused by mutations in FOXC2. ![]() |
4. |
Finegold DN et al. (2001) Truncating mutations in FOXC2 cause multiple lymphedema syndromes. ![]() |
5. |
Emberger JM et al. (1979) [Deaf-mutism, lymphedema of the lower limbs and hematological abnormalities (acute leukemia, cytopenia) with autosomal dominant transmission]. ![]() |
6. |
None () //// ![]() |
7. |
None (1961) [Observations on Nonne-Milroy-Meige syndrome]. ![]() |
8. |
Avasthey P et al. (1968) Primary pulmonary hypertension, cerebrovascular malformation, and lymphoedema feet in a family. ![]() |
9. |
None (1966) Yellow nails, lymphoedema, and pleural effusions. ![]() |
10. |
Figueroa AA et al. (1983) Meige disease (familial lymphedema praecox) and cleft palate: report of a family and review of the literature. ![]() |
11. |
Herbert FA et al. (1983) Hereditary late-onset lymphedema with pleural effusion and laryngeal edema. ![]() |
12. |
Wheeler ES et al. (1981) Familial lymphedema praecox: Meige's disease. ![]() |
13. |
Andersson HC et al. (1995) Lymphangiosarcoma in late-onset hereditary lymphedema: case report and nosological implications. ![]() |
14. |
OMIM.ORG article Omim 153200![]() |
15. |
Orphanet article Orphanet ID 77240![]() |